Open AccessDeterminants of Risk of Spontaneous Abortions in the First Trimester of Pregnancy
Author(s) -
Fabio Parazzini,
Liliane Chatenoud,
Luca Tozzi,
G Benzi,
Daniela Dal Pino,
Luigi Fedele
Publication year - 1997
Publication title -
epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 173
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/00001648-199710000-00012
Subject(s) - odds ratio , confidence interval , medicine , quartile , population , logistic regression , pregnancy , rectum , physiology , case control study , demography , biology , environmental health , genetics , sociology
Several factors, such as socioeconomic status, obstetrical and menstrual history, and contraceptive methods, have been associated with risk of spontaneous abortion. We conducted a hospital case-control study to analyze risk factors for spontaneous abortion during the first trimester. Cases were 782 women admitted for spontaneous abortion. Controls included 1,543 women who gave birth at term in the same hospitals. Adjusted odds ratios (ORs) for spontaneous abortion were 0.9 and 0.6, respectively, for women reporting 7-11 and > or = 12 years of schooling, compared with women reporting < 7 years of education. A history of pelvic inflammatory disease increased the odds ratio fivefold [OR = 5.1; 95% confidence interval (CI) = 1.0-26.2]. The OR for spontaneous abortion was 1.7 (95% CI = 1.4-2.1) in women reporting previous spontaneous abortions.