Open AccessDose-Dependent Impairment of Collagen Deposition by Topical Granulocyte-Macrophage Colony-Stimulating Factor in Human Experimental Wounds
Author(s) -
Lars Nannestad Jørgensen,
Magnus S. Ågren,
Søren Munk Madsen,
Finn Kallehave,
Faranak Vossoughi,
Annette Rasmussen,
Finn Gottrup
Publication year - 2002
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200211000-00020
Subject(s) - granulation tissue , hydroxyproline , medicine , granulocyte macrophage colony stimulating factor , connective tissue , cellular infiltration , wound healing , saline , histology , pathology , granulocyte , andrology , immunology , inflammation , cytokine
The authors studied the dose-dependent effect of topically administered granulocyte-macrophage colony-stimulating factor (GM-CSF) on the connective tissue response using an experimental repair model in surgical patients.