Open AccessHypertonic Saline Resuscitation of Hemorrhagic Shock Diminishes Neutrophil Rolling and Adherence to Endothelium and Reduces In Vivo Vascular Leakage
Author(s) -
José L. Pascual,
Lorenzo Ferri,
Andrew Seely,
Giuseppina Campisi,
Prosanto Chaudhury,
Betty Giannias,
David C. Evans,
Tarek Razek,
René P. Michel,
Nicolas V. Christou
Publication year - 2002
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200211000-00014
Subject(s) - resuscitation , medicine , hypertonic saline , cremaster muscle , shock (circulatory) , in vivo , vascular permeability , intravital microscopy , endothelium , hemorrhagic shock , anesthesia , pharmacology , microcirculation , pathology , biology , microbiology and biotechnology
To evaluate the in vivo effects of hypertonic saline (HTS) resuscitation on the interactions of endothelial cells (ECs) and polymorphonuclear neutrophils (PMNs) and vascular permeability after hemorrhagic shock.