Open AccessVarious Penetrance of Familial Medullary Thyroid Carcinoma in Patients With RET Protooncogene Codon 790/791 Germline Mutations
Author(s) -
Guido Fitze,
Mandy Schierz,
Jan Bredow,
H. D. Saeger,
D. Roesner,
Hans K. Schackert
Publication year - 2002
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200211000-00006
Subject(s) - penetrance , germline mutation , medicine , germline , thyroidectomy , genetics , mutation , thyroid carcinoma , thyroid , medullary carcinoma , gene , cancer research , phenotype , biology
To describe a genotype-phenotype correlation in MEN2 families with germline mutations of codons 790/791 and discuss options for the therapeutic management of gene carriers.