Open AccessSulfonylurea Receptor Knockout Causes Glucose Intolerance in Mice That is Not Alleviated by Concomitant Somatostatin Subtype Receptor 5 Knockout
Author(s) -
Michael Norman,
Stefan Moldovan,
Victor Seghers,
Xiaoping Wang,
Francesco J. DeMayo,
F. Charles Brunicardi
Publication year - 2002
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200206000-00003
Subject(s) - medicine , endocrinology , sulfonylurea , type 2 diabetes , somatostatin , insulin , knockout mouse , diabetes mellitus , receptor
To examine the long-term effects of Sur KO, SSTR5 KO, and double Sur/SSTR5 KO on insulin secretion and glucose regulation.