Open AccessInosine Exerts a Broad Range of Antiinflammatory Effects in a Murine Model of Acute Lung Injury
Author(s) -
Lucas Liaudet,
Jon Mabley,
Pál Pacher,
László Virág,
Francisco Garcia Soriano,
Anita Marton,
György Haskó,
Edwin A. Deitch,
Csaba Szabó
Publication year - 2002
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200204000-00016
Subject(s) - proinflammatory cytokine , inosine , myeloperoxidase , medicine , bronchoalveolar lavage , tumor necrosis factor alpha , chemokine , immunology , pharmacology , inflammation , lung , adenosine
To investigate the effects of inosine on the acute lung inflammation induced by lipopolysaccharide (LPS) in vivo and on the activation and cytotoxicity elicited by proinflammatory cytokines on human lung epithelial (A549) cells in vitro.