Open AccessDetection of Micrometastatic Tumor Cells in pN0 Lymph Nodes of Patients With Completely Resected Nonsmall Cell Lung Cancer
Author(s) -
Zhuoshi Li,
Toshihiro Osaki,
Tsunehiro Oyama,
Masatoshi Inoue,
Mantaro Kodate,
Kazuhito Dobashi,
Takuji Oka,
Kosei Yasumoto
Publication year - 2002
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200201000-00017
Subject(s) - micrometastasis , medicine , lymph , cytokeratin , immunohistochemistry , pathology , lung cancer , lymph node , metastasis , stage (stratigraphy) , carcinoma , cancer , biology , paleontology
To detect occult micrometastatic tumor cells in pN0 lymph nodes of nonsmall cell lung cancer (NSCLC) by a combination of cytokeratin and p53 immunohistochemistry staining, and to evaluate the relation between the micrometastasis in pN0 lymph nodes and the prognosis of patients with completely resected stage 1 NSCLC.