Open AccessExpression of Adrenocorticotropin Receptor Gene in Adrenocortical Adenomas From Patients With Cushing Syndrome: Possible Contribution for the Autonomous Production of Cortisol
Author(s) -
Tsuneo Imai,
Devanand Sarkar,
Arihiro Shibata,
Hiroomi Funahashi,
Takako Morita-Matsuyama,
Toyone Kikumori,
Sachiko Ohmori,
Hisao Seo
Publication year - 2001
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200107000-00013
Subject(s) - endocrinology , medicine , acth receptor , adrenocorticotropic hormone , cushing syndrome , adenoma , receptor , gene expression , biology , hormone , gene , biochemistry
To examine whether inhibition of endogenous adrenocorticotropin (ACTH) secretion in patients with Cushing syndrome affects the expression of the ACTH receptor (ACTH-R) gene in adrenocortical adenoma and attached atrophic normal gland.