Open AccessHigh-Throughput Drug Screening of the DPC4 Tumor-Suppressor Pathway in Human Pancreatic Cancer Cells
Author(s) -
Taylor A. Sohn,
Gloria H. Su,
Byungwoo Ryu,
Charles J. Yeo,
Scott E. Kern
Publication year - 2001
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200105000-00014
Subject(s) - signal transduction , transfection , luciferase , cancer research , pancreatic cancer , biology , reporter gene , medicine , gene , microbiology and biotechnology , cancer , genetics , gene expression
To screen a library of small chemicals for compounds that activate the DPC4 signal transduction pathway in a human pancreatic cancer cell line.