Open AccessGut-Derived Sepsis Occurs When the Right Pathogen With the Right Virulence Genes Meets the Right Host
Author(s) -
John C. Alverdy,
Christopher Holbrook,
Flavio Rocha,
Louis Seiden,
Richard Licheng,
Kan Wu,
Mark W. Musch,
Eugene B. Chang,
Dennis E. Ohman,
Sanj Suh
Publication year - 2000
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200010000-00003
Subject(s) - cecum , virulence , microbiology and biotechnology , pseudomonas aeruginosa , bacterial adhesin , medicine , in vivo , sepsis , pathogen , immunology , biology , bacteria , gene , biochemistry , genetics
To define the putative role of the PA-I lectin/adhesin, a binding protein of Pseudomonas aeruginosa, on lethal gut-derived sepsis after surgical stress, and to determine if this protein is expressed in vivo in response to physical and chemical changes in the local microenvironment of the intestinal tract after surgical stress.