Open AccessActivated Protein C Reduces the Ischemia/Reperfusion-Induced Spinal Cord Injury in Rats by Inhibiting Neutrophil Activation
Author(s) -
K Hirose,
Kenji Okajima,
Yuji Taoka,
Mitsuhiro Uchiba,
Hirofumi Tagami,
K. Nakano,
Junichi Utoh,
Hiroaki Okabe,
Nobuo Kitamura
Publication year - 2000
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200008000-00018
Subject(s) - medicine , ischemia , anesthesia , myeloperoxidase , spinal cord , reperfusion injury , h&e stain , spinal cord injury , pharmacology , pathology , inflammation , staining , psychiatry
To examine whether activated protein C (APC) reduces spinal cord injury in rats by inhibiting neutrophil activation after the transient ischemia.