Open AccessDisruption of TGFβ Signaling Pathways in Human Pancreatic Cancer Cells
Author(s) -
Diane M. Simeone,
T. M. Pham,
Craig D. Logsdon
Publication year - 2000
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200007000-00011
Subject(s) - medicine , pancreatic cancer , signal transduction , transforming growth factor , cancer research , cancer , microbiology and biotechnology , biology
To investigate whether transforming growth factor beta (TGFbeta) signaling is disrupted in human pancreatic cancer cells, and to study the role of TGFbeta receptors and Smad genes.