Open AccessNeoadjuvant Interleukin-12 Immunogene Therapy Protects Against Cancer Recurrence After Liver Resection in an Animal Model
Author(s) -
William R. Jarnagin,
Keith A. Delman,
David A. Kooby,
Stephen Mastorides,
Jonathan S. Zager,
Murray F. Brennan,
Leslie H. Blumgart,
Howard J. Federoff,
Yuman Fong
Publication year - 2000
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200005000-00017
Subject(s) - medicine , immune system , in vivo , malignancy , neoadjuvant therapy , cd8 , cancer , hepatectomy , genetic enhancement , cancer research , immunotherapy , pathology , immunology , resection , surgery , biology , gene , biochemistry , microbiology and biotechnology , breast cancer
To evaluate the neoadjuvant use of a herpes simplex viral (HSV) amplicon vector expressing the murine interleukin-12 (IL-12) gene.