Open AccessClinical Significance of p53 Mutations in Adenocarcinoma of the Esophagus and Cardia
Author(s) -
Adrian P. Ireland,
Darryl Shibata,
Para Chandrasoma,
Reginald V. Lord,
Jeffrey H. Peters,
Tom R. DeMeester
Publication year - 2000
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200002000-00005
Subject(s) - esophagus , adenocarcinoma , medicine , mutation , mutant , gene , exon , cancer research , barrett's esophagus , esophagogastric junction , clinical significance , esophageal disease , pathology , polymerase chain reaction , cancer , biology , genetics
To compare the frequency and spectrum of p53 gene mutations in adenocarcinomas of the esophagus and cardia and to compare clinical and pathologic features in patients with p53 mutant and nonmutant cancers.