Open AccessTotal Warm Ischemia and Reperfusion Impairs Flow in All Rat Gut Layers but Increases Leukocyte–Vessel Wall Interactions in the Submucosa Only
Author(s) -
R.J. Beuk,
Erik Heineman,
G. J. Tangelder,
Josine Quaedackers,
William H. Marks,
Joshua M. Lieberman,
Mirjam G.A. oude Egbrink
Publication year - 2000
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-200001000-00014
Subject(s) - medicine , ischemia , submucosa , superior mesenteric artery , reperfusion injury , enterocyte , perfusion , pathology , microcirculation , intravital microscopy , small intestine , in vivo , blood flow , mesenteric ischemia , anatomy , biology , microbiology and biotechnology
To study the effect of warm ischemia and reperfusion (I/R) on local perfusion and leukocyte-vessel wall interactions in vivo in all small bowel layers, and to quantify small bowel tissue injury histologically and by measuring intestinal fatty acid binding protein (I-FABP) release from the enterocytes.