Open AccessRelation of a TNF Gene Polymorphism to Severe Sepsis in Trauma Patients
Author(s) -
Matthias Majetschak,
Sascha Flohé,
U. Obertacke,
Jörg Schröder,
K. H. Staubach,
D. Nast-Kolb,
Schade Fu,
Frank Stüber
Publication year - 1999
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-199908000-00011
Subject(s) - sepsis , medicine , genotype , gastroenterology , odds ratio , allele , immunology , injury severity score , restriction fragment length polymorphism , gene , poison control , biology , genetics , injury prevention , environmental health
To investigate the relation of the biallelic Nco1 restriction fragment length polymorphism in the first intron of the tumor necrosis factor (TNF) beta gene with the development of severe sepsis in multiply injured patients.