Open AccessImproved Survival and Reduction in Local Failure Rates After Preoperative Radiotherapy
Author(s) -
Mikael Dahlberg,
Bengt Glimelius,
Lars Påhlman
Publication year - 1999
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-199904000-00007
Subject(s) - medicine , radiation therapy , survival rate , colorectal cancer , cancer , surgery , stage (stratigraphy) , paleontology , biology
The Swedish Rectal Cancer Trial (SRCT) demonstrated that a short-term regimen of high-dose preoperative radiotherapy (5 x 5 Gy) not only reduced the local recurrence rates but also improved the overall survival rate. This compelling evidence will have a significant impact on the primary treatment of rectal cancer. The authors' aim was to explore the representativeness of the study.