Open AccessTransfection of the Type II TGF-β Receptor Into Colon Cancer Cells Increases Receptor Expression, Inhibits Cell Growth, and Reduces the Malignant Phenotype
Author(s) -
Sally L. D. MacKay,
Troy Auffenberg,
Cynthia L. Tannahill,
Riadh Ksontini,
Michael D. Josephs,
Monika Nowak,
Lyle L. Moldawer,
Edward M. Copeland
Publication year - 1998
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-199806000-00001
Subject(s) - transfection , microbiology and biotechnology , medicine , cell growth , cell culture , cancer research , biology , genetics
To determine if transfection of SW48 colon cancer cells with the type II transforming growth factor-beta (TGF-beta) receptor restores growth inhibition and reverses the in vitro and in vivo malignant phenotype.