Open AccessUnopposed Interleukin-1 is Necessary for Increased Plasma Cytokine and Eicosanoid Levels to Develop in Severe Sepsis
Author(s) -
Gus J. Slotman,
James Quinn,
Philip Wry,
Collin Brathwaite,
Bruce Friedman
Publication year - 1997
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-199707000-00011
Subject(s) - medicine , sepsis , cytokine , eicosanoid , immunology , interleukin , intensive care medicine , biochemistry , enzyme , arachidonic acid , chemistry
The purpose of the study was to identify the changes in plasma prostaglandin, leukotriene, and cytokine levels during clinical severe sepsis for which interleukin-1 was necessary.