Open AccessExpression of MAGE Genes in Human Colorectal Carcinoma
Author(s) -
Masaki Mori,
Hiroshi Inoue,
Koshi Mimori,
Kenji Shibuta,
Kanji Baba,
Hiroaki Nakashima,
Masanobu Haraguchi,
K. Tsuji,
Hiroaki Ueo,
Graham F. Barnard,
Tsuyoshi Akiyoshi
Publication year - 1996
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-199608000-00011
Subject(s) - demethylating agent , medicine , gene , colorectal cancer , cancer research , immunotherapy , antigen , metastasis , reverse transcription polymerase chain reaction , cytotoxic t cell , carcinoma , gene expression , cancer , immunology , pathology , biology , promoter , genetics , in vitro
The human genes MAGE-1 and -3 encode tumor-specific peptide antigens, which are recognized by autologous cytotoxic T lymphocytes. The antigens coded by those genes may be useful for cancer immunotherapy. There is, however, little information on the expression of these genes in human colorectal carcinomas.