Open AccessIntravenous Contrast Medium Aggravates the Impairment of Pancreatic Microcirculation in Necrotizing Pancreatitis in the Rat
Author(s) -
Jan Schmidt,
Hubert G. Hotz,
Thomas Foitzik,
Eduard Ryschich,
H. J. Buhr,
Andrew L. Warshaw,
Christian Herfarth,
E. Klar
Publication year - 1995
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-199503000-00007
Subject(s) - medicine , microcirculation , contrast medium , perfusion , pancreatitis , saline , intravital microscopy , necrosis , pancreas , blood flow , acute pancreatitis , pathology , nuclear medicine , radiology
Previous reports demonstrated that radiographic contrast medium, as used in contrast-enhanced computed tomography, increases acinar necrosis and mortality in experimental pancreatitis. The authors studied the possibility that these changes may be related to an additional impairment of pancreatic microcirculation.