Open AccessNormalization of Tumor-Induced Increases in Hepatic Amino Acid Transport After Surgical Resection
Author(s) -
N. Joseph Espat,
Barrie P. Bode,
D. Scott Lind,
Edward M. Copeland,
Wiley W. Souba
Publication year - 1995
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-199501000-00006
Subject(s) - glutamine , medicine , arginine , amino acid , fibrosarcoma , endocrinology , pathology , biochemistry , biology
The liver of the host with cancer requires increased amounts of amino acids to support the synthesis of glucose and key defense proteins. To study the effect of the growing tumor on hepatic amino acid uptake, the authors measured hepatic transport activity in tumor-bearing rats and in rats at various times after tumor resection.