Open AccessEfficacy of Rapamycin and FK 506 in Prolonging Rat Hind Limb Allograft Survival
Author(s) -
Michael J. Fealy,
William S. Umansky,
Kyle D. Bickel,
John J. Nino,
Randal E. Morris,
Barry H. J. Press
Publication year - 1994
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-199401000-00014
Subject(s) - medicine , hindlimb , sirolimus , surgery , urology
Graft rejection and the toxicity of current immunosuppressive regimens preclude the application of microsurgical advances to transplantation of limbs or other nonessential parts. If limb transplantation is to become a clinical reality, newer, safer, more effective immunosuppressive agents are needed.