
Total Parathyroidectomy with Forearm Autograft for Secondary Hyperparathyroidism in Chronic Renal Failure
Author(s) -
Hiroshi Takagi,
Yoshihiro Tominaga,
Yuji Tanaka,
Kazuharu Uchida,
A Orihara,
Nobuo Yamada,
Masahiro Kawai,
Shuji Hayashi,
N. Taira,
T Kano
Publication year - 1988
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-198811000-00016
Subject(s) - medicine , forearm , parathyroid hormone , secondary hyperparathyroidism , parathyroidectomy , supernumerary , hyperparathyroidism , chronic renal failure , hemodialysis , urology , surgery , anatomy , calcium
One hundred twenty-eight patients with chronic renal failure and secondary hyperparathyroidism underwent total parathyroidectomy with forearm autograft. Postoperative clinical improvement was remarkable. In all cases, the grafted tissue functioned well, and reimplantation of the cryopreserved parathyroid tissues was unnecessary. Intact 1-84 parathyroid hormone was more sensitive than C-terminal parathyroid hormone in parathyroid hormone level (PTH) gradient assays of grafted and nongrafted forearm. The study of hypocalcemia was also helpful in obtaining more distinct PTH gradients. Five of 119 patients had supernumerary parathyroid glands (4.2%), which preoperative noninvasive image diagnosis of parathyroid glands was helpful in detecting.