Open AccessThe Relationship Between Primary Hyperparathyroidism and Diabetes Mellitus
Author(s) -
Michael P. Ban,
Jon A. van Heerden,
P. J. Palumbo,
Duane M. Ilstrup
Publication year - 1988
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-198804000-00010
Subject(s) - medicine , primary hyperparathyroidism , parathyroidectomy , diabetes mellitus , insulin , hypoparathyroidism , type 2 diabetes mellitus , hyperparathyroidism , thyroidectomy , euthyroid , surgery , endocrinology , thyroid , parathyroid hormone , calcium
Previous reports have suggested that control of diabetes improves after successful parathyroidectomy for primary hyperparathyroidism. To investigate this proposition further, a review was made of all insulin-requiring diabetics undergoing curative parathyroidectomy at the Mayo Clinic between 1970 and 1984 (36 patients). All contemporary insulin-requiring diabetics undergoing thyroidectomy for benign euthyroid disease served as a control group (34 patients). One patient in each group had type I diabetes mellitus, and the remainder had type II diabetes mellitus. Preoperative insulin requirements, insulin requirements at follow-up, and change in insulin requirements did not differ significantly between the two groups. This study suggests that parathyroidectomy does not lead to a statistically significant reduction in the insulin requirements of diabetic patients with primary hyperparathyroidism and that coexistent type II diabetes mellitus should not be considered a further indication for parathyroidectomy in patients with primary hyperparathyroidism.