Open AccessAdjuvant Chemotherapy After Surgery and Radiation for Stage III and IV Head and Neck Cancer
Author(s) -
Andrew T. Huang,
T. Boyce Cole,
Robert I. Fishburn,
S B Jelovsek
Publication year - 1984
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-198408000-00013
Subject(s) - medicine , chemotherapy , adjuvant , surgery , stage (stratigraphy) , radiation therapy , adjuvant chemotherapy , head and neck , head and neck cancer , cancer , adjuvant radiotherapy , breast cancer , paleontology , biology
Twenty consecutive patients with Stage III and IV squamous head and neck cancer were treated with surgery, radiation, and adjuvant multiagent chemotherapy. Eleven other patients who were referred for local recurrent disease were treated with second surgery or radiation and also with adjuvant chemotherapy. The actuarial survival of these two groups of patients combined (N = 31) was 87% at 6 years. Four patients died of recurrent cancer (two in each group), six of unrelated causes during a 6-year follow-up. The side effects of adjuvant chemotherapy were mild to moderate and of short duration.