Open AccessThe Coexistence of Renal Artery Stenosis and Pheochromocytoma
Author(s) -
Fontaine S. Hill,
H. Peter Jander,
Tariq M. Murad,
Arnold G. Diethelm
Publication year - 1983
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-198304000-00019
Subject(s) - medicine , pheochromocytoma , renal artery stenosis , pathophysiology , renal artery , blood pressure , paraganglioma , stenosis , etiology , renal artery obstruction , cardiology , plasma renin activity , secondary hypertension , renin–angiotensin system , kidney , radiology
The coexistence of renal artery stenosis and pheochromocytoma has been recognized since 1958 and a total of 36 patients reported. This article provides an additional patient with an extra adrenal pheochromocytoma and fibrous bands constricting the left renal artery. Hypertension was confirmed to occur from both excess catecholamine production and hyperreninemia from the left kidney. Surgical removal of the functioning paraganglioma and correction of the renal artery stenosis restored the postoperative plasma catecholamine, renin, and blood pressure to normal. A literature review confirmed the coexistence of these two lesions but failed to provide a common etiology to explain the pathophysiology encountered. However, when the two diseases occur simultaneously, both must be diagnosed accurately and treated in a definitive manner.