Open AccessA Biomechanical, Scanning Electron, and Light Microscopic Evaluation
Author(s) -
Kevin C. Hanel,
Charles J. McCabe,
William M. Abbott,
J T Fallon,
Joseph Megerman
Publication year - 1982
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-198204000-00012
Subject(s) - medicine , scanning electron microscope , anastomosis , in vivo , biomedical engineering , femoral artery , electron microscope , microscopy , anatomy , artery , pathology , nuclear medicine , surgery , optics , composite material , materials science , biology , physics , microbiology and biotechnology
Two currently available brands of PTFE grafts (Goretex and Impra) were studied in a canine femoral artery model to determine whether changes in the manufacturing processes of the two grafts, which increased their strength, had altered the biophysical properties and the histological reactivity of either graft. Both grafts were found to be similar except for differences in their suturability. Their in vivo dynamic compliances were almost identical (1.2 +/- 0.35 vs. 1.2 +/- 0.45). (Scanning electron microscopy showed endothelialization of the grafts only adjacent to the anastomoses, and light microscopy demonstrated similar degrees of histologic incorporation by the host tissues, though of slower tempo than that previously described. These results are examined and discussed with regard to the suitability of this model for characterizing new arterial prostheses of small to medium diameter.