Open AccessRenal Transplantation After Thoracic Duct Drainage
Author(s) -
Jay C. Fish,
H Sarles,
August R. Remmers,
Courtney M. Townsend,
Jason D. Bell,
M. Wayne Flye
Publication year - 1981
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-198106000-00010
Subject(s) - medicine , cadaveric spasm , surgery , immunosuppression , thoracic duct , transplantation , duplex (building) , urology , pathology , lymphatic system , dna , biology , genetics
Forty-seven patients treated by at least 28 days of thoracic duct drainage (TDD) before cadaveric renal transplant are compared with 63 patients treated with standard immunosuppression. The TDD patients were begun on half the dosage of steroids, and at 30 days were receiving approximately two-thirds the dose that the non-TDD patients received. Acute rejection occurred in 35% of the TDD group, as compared with 61% of the non-TDD group. Graft survival in the TDD patients was twice as good as the non-TDD patients at all time intervals. The patient survival rates were not significantly different between the two groups. TDD pretransplant favorably affects cadaveric renal allograft survival for at least five years.