Open AccessHistologic Appearances of Endoscopic Gastric Mucosal Biopsies 10–20 Years After Partial Gastrectomy
Author(s) -
Karel Geboes,
Paul Rutgeerts,
L Broeckaert,
Gaston Vantrappen,
Valeer Desmet
Publication year - 1980
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-198008000-00008
Subject(s) - medicine , dysplasia , foveolar cell , intestinal metaplasia , gastroenterology , gastrectomy , metaplasia , gastritis , endoscopy , hyperplasia , biopsy , gastric mucosa , cancer , stomach
Fifty-six symptomatic patients, who had had a partial gastrectomy 10--24 years previously for benign disease, were examined by endoscopy and multiple mucosal biopsies. No patient had a completely normal gastric mucosa. Varying degrees of gastritis, intestinal metaplasia, foveolar hyperplasia and dysplasia were seen. Seventeen patients (30%) had extensive areas of dysplasia associated with acute or chronic inflammation. Severe dysplasis, however, was detected in only one case. In five patients a "diffuse type" carcinoma of the gastric stump was found. While it is generally accepted that significant dysplasia (moderate or severe dysplasis) is premalignant, the degree of risk is unknown. This makes management of individual patients difficult.