Open AccessClinical Manifestations of Infections with Herpesviruses After Kidney Transplantation
Author(s) -
S Naraqi,
Olga Jonasson,
George Gee Jackson,
Herbert M. Yamashiroya
Publication year - 1978
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-197808000-00017
Subject(s) - medicine , immunosuppression , kidney transplantation , asymptomatic , mononucleosis , immunology , pneumonia , transplantation , virus
Herpesviruses infections occur commonly following kidney transplantation and immunosuppression, and contribute substantially to morbidity in the transplant recipient. In this prospective study, stomatitis, mononucleosis, hepatitis, or interstitial pneumonia occurred in 24 of 30 patients (80%) as a result of reactivation of latent herpesvirus infections, but the majority of these syndromes were self-limited and the infections were often asymptomatic. Rejection occurred significantly more frequently in CMV-infected patients, but a distinct causal relationship cannot be deduced.