Open AccessFollow-up Studies of Radical Resection for Pancreaticoduodenal Cancer
Author(s) -
Toshio Sato,
Yoichi Saitoh,
Noboru Noto,
Seiki Matsuno
Publication year - 1977
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-197711000-00007
Subject(s) - medicine , pancreaticoduodenectomy , ampulla of vater , carcinoma , ampulla , pancreas , head of pancreas , lymph node , bile duct , gastroenterology , lesion , common bile duct , surgery
In a study of 66 patients with pancreaticoduodenal cancer with pancreaticoduodenectomy, there were five (7.5%) hospital deaths. Five-year survival rates were 7.8% in 20 patients with carcinoma of the head of the pancreas, 16.7% in 31 patients with carcinoma of the bile duct, and 38.5% in 15 patients with carcinoma of the ampulla of Vater. Fecal fat loss measured was 10 g or less per day in nine of 12 patients. Of the 19 patients having glucose tolerance tests, 13 showed abnormalities including the two who were diabetic. Operative findings which were indicative of a poor prognosis included lymph node metastases, macroscopic invasion of the tumor into the pancreatic capsule in patients with carcinoma of the head of the pancreas, the size of the tumor in those with carcinoma of the common bile duct, and direct invasion of the lesion into the pancreas in patients with carcinoma of the ampulla of Vater.