Open AccessThe Accuracy of Predicting Lymph Node Metastases in Malignant Melanoma by Clinical Examination and Microstaging
Author(s) -
L Goldman,
W P Clark,
Evelina A. Bernardino,
Ann M. Ainsworth
Publication year - 1976
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-197611000-00002
Subject(s) - medicine , melanoma , lymph node , lymph , regimen , disease , prospective cohort study , oncology , pathology , cancer research
Since 1971, a prospective treatment regimen for primary cutaneous malignant melanoma performed by a single clinician has revealed the following early observations: 1) A significantly higher number of females with level II disease; 2) No recurrences or metastases to date in 29 patients with level II lesions treated by appropriate surgery; 3) The apparent clinical predictability of lymph node metastases in the group microstaged at level III. 4) An inability to predict lymph node metastases (or their delayed development) in patients with level IV disease; 5) A correlation between lymph node metastases and the development of disseminated disease.