Open AccessIn Situ Preservation of Cadaver Kidneys for Transplantation
Author(s) -
Raúl GarcíaRinaldi,
Edward A. Lefrak,
W. Wilson Defore,
Louis Feldman,
George P. Noon,
Joseph A. Jachimczyk,
Michael E. DeBakey
Publication year - 1975
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-197511000-00008
Subject(s) - medicine , cadaver , warm ischemia , transplantation , nephrectomy , catheter , surgery , lumen (anatomy) , kidney transplantation , kidney , ischemia , reperfusion injury
Many kidneys obtained from cadaver donors undergoing sudden cardiac arrest cannot be transplanted due to the long periods of warm ischemia from the moment of arrest to nephrectomy. A double-ballon-triple-lumen catheter for the rapid in situ preservation of cadaver kidneys has been designed. Used in combination with equipment routinely found in any hospital, it can cool human kidneys in situ to 10-15 C and maintain this temperature until nephrectomy can be performed. Kidenys preserved with this catheter have functioned after transplantation into suitable recipients. This report describes the design and laboratory evaluation of this new device, its clinical effectiveness and technique of insertion.