Open AccessIs Childhood Thyroid Cancer a Lethal Disease ?
Author(s) -
Joseph A. Buckwalter,
Colin G. Thomas,
Joel B. Freeman
Publication year - 1975
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-197505000-00018
Subject(s) - medicine , pathological , thyroid , thyroid carcinoma , thyroid cancer , disease , follicular phase , oncology , follicular carcinoma , cancer , pediatrics , papillary carcinoma
The clinical, pathological, surgical, postoperative findings and survivorship of 58 patients younger and 513 patients older than 21 years at the time of diagnosis with thyroid neoplasms are reported. The younger patients have a predominance of well differentiated carcinomas which are more likely to be follicular. The lesions tend to be more advanced at the time of diagnosis, are treated by more aggressive surgery in the younger patients and are associated with a much better prognosis. Lack of progression of well to poorly differentiated neoplasms and a greater sensitivity to and dependence upon TSH in young patients, are two factors which may contribute to the striking difference in the prognosis of well differentiated thyroid carcinoma related to age.