Open AccessA Technique for Estimating the Position of the Oxygen-Hemoglobin Dissociation Curve
Author(s) -
Peter C. Canizaro,
James L. Nelson,
John L. Hennessy,
Peter B. Bright
Publication year - 1974
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/00000658-197409000-00018
Subject(s) - medicine , oxygen–haemoglobin dissociation curve , hemoglobin , oxygen , dissociation (chemistry) , position (finance) , chemistry , organic chemistry , finance , economics
A nomogram was constructed which allows estimation of the P(50) value from the Po(2) and per cent O(2) saturation of a single venous blood sample. There was excellent correlation between 50 estimated P(50) values obtained in 27 severely ill patients when compared with P(50) values determined from constructed OH-DC's (correlation coefficient 0.92). The mean of the differences between the estimated and determined P(50) values was 1.5 mm Hg with a standard deviation of +/-1.1, and the maximum difference was 4 mm Hg.