Open AccessThe Effect of Noise on the Bispectral Index During Propofol Sedation
Author(s) -
Dae Woo Kim,
Hae Keum Kil,
Paul F. White
Publication year - 2001
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1097/00000539-200111000-00022
Subject(s) - propofol , bispectral index , sedation , medicine , anesthesia , noise (video) , crossover study , confidence interval , image (mathematics) , alternative medicine , pathology , artificial intelligence , computer science , placebo
Because noise in the operating room has been alleged to interfere with the ability to sedate patients before surgery, we evaluated the effect of noise on the Bispectral index (BIS) value during propofol sedation. Thirty unpremedicated patients were studied before the start of surgery while receiving propofol sedation on two separate occasions according to a randomized, crossover protocol design. After achieving a stable baseline BIS value of either 75 or 80 with a target-controlled infusion of propofol, an external sound source administered noise at 50, 80, 110, and 120 dB. The changes in the BIS value were recorded over a 1-min interval at each noise level. In the BIS 75 group, increasing levels of noise did not significantly alter the BIS value. However, in the BIS 80 group, the BIS values at 80, 110, and 120 dB were significantly higher compared to the value at 50 dB. In conclusion, experimental noise increases the BIS and appears to have a greater effect on the BIS value at "lighter" levels of propofol sedation.