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Focus on vision: 3 decades of remarkable contributions to biology and medicine
Author(s) -
Palczewski Krzysztof
Publication year - 2011
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fj.11-0202ufm
Subject(s) - retinal , photoisomerization , pillar , neuroscience , biology , biochemistry , engineering , structural engineering , isomerization , catalysis
T he FASEB J ournal is a pillar among biomedical publications, contributing greatly by disseminating the results of vision research during its lifetime. Progress over this period has been remarkable. George Wald (1) provided the first chemical understanding of the fundamental processes governing vision: the photoisomerization of 11‐cís‐retinal to all‐írαrø‐retinal and the enzymatic regeneration of this chro‐mophore. Contributions of this extraordinary scientist (2, 3) set the stage for discoveries ranging from gross recording of various electrical responses to light to elucidation of signal transduction at a structural level, and from characterization of retinal diseases to successful treatments. FASEB J. 25, 439–443 (2011). www.fasebj.org