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New surprises in genetic coding and how an ingenious experiment was almost scooped, by evolution
Author(s) -
Pederson Thoru
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fj.06-0902ufm
Subject(s) - coding (social sciences) , genetic code , transfer rna , computer science , computational biology , rna , biology , theoretical computer science , genetics , amino acid , mathematics , gene , statistics
SUMMARY In 1962, one of the most creative and cogent experiments on the protein coding problem was published. Now it has been discovered that archaebacteria had been doing a related kind of “experiment” all along. Both involve a trick: changing an amino acid that is already attached to a “correct” transfer RNA.