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Ribosomal RNA: a key to phylogeny
Author(s) -
Olsen Gary J.,
Woese Carl R.
Publication year - 1993
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.7.1.8422957
Subject(s) - phylogenetics , ribosomal rna , phylogenetic tree , biology , evolutionary biology , computational biology , genome , rna , genetics , gene
As molecular phylogeny increasingly shapes our understanding of organismal relationships, no molecule has been applied to more questions than have ribosomal RNAs. We review this role of the rRNAs and some of the insights that have been gained from them. We also offer some of the practical considerations in extracting the phylogenetic information from the sequences. Finally, we stress the importance of comparing results from multiple molecules, both as a method for testing the overall reliability of the organismal phylogeny and as a method for more broadly exploring the history of the genome.— Olsen, G. J., Woese, C. R. Ribosomal RNA: a key to phylogeny. FASEB J. 7: 113‐123; 1993.