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Oncogenes in growth and development 1
Author(s) -
Travali Salvatore,
Koniecki Janice,
Petralia Salvatore,
Baserga Renato
Publication year - 1990
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.4.14.2227212
Subject(s) - cell growth , function (biology) , biology , second messenger system , microbiology and biotechnology , cell cycle , proto oncogenes , cell function , cell , genetics , signal transduction , oncogene
Oncogenes play a major role in the control of proliferation in animal cells. Because the growth of cell populations is regulated by the stimulatory and inhibitory growth factors in the environment, we have attempted in this review to relate the function of oncogenes to the mechanism of action of growth factors. This correlation allows a description of the cell cycle that rests on a molecular basis and in which proto‐oncogenes figure prominently as the cellular messengers of the environmental growth stimuli.— T ravali , S.; K oniecki , J.; P etralia , S.; B aserga , R. Oncogenes in growth and development. FASEB J. 4: 3209‐3214; 1990.