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Estimation of Growth Model Parameters for Mini Pig Breeds
Author(s) -
Jo Hyunwoong,
Lee Sang Chul,
Kim Dae Cheol,
Kim Beob Gyun
Publication year - 2017
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.31.1_supplement.lb299
Subject(s) - crossbreed , breed , large white , biology , zoology , body weight , domestic pig , miniature pig , veterinary medicine , transplantation , gompertz function , medicine , geography , mathematics , statistics , endocrinology , genetics , forestry
Pigs are used as models for human because of the similarities in digestive systems. Mini pigs are often used in nutritional studies as well as organ transplantation studies. The relatively small pigs are easier to handle than large pigs. An accurate estimation of body weight of mini pigs is important in animal experimentation. The objective of this work was develop growth models for two mini pig breeds: a M‐Pig ® breed originating from Korean Jeju Island native pigs (Cronex Co., Ltd., Hwaseong, Republic of Korea) and Micro‐pig ® (Medi Kinetics Co., Ltd., Pyeongteak, Republic of Korea). The M‐Pig ® is developed by selecting Jeju Island native pigs with slow growth rate for the purpose of human organ transplantation research. A total 680 body weight data ranging from 0.8 to 63.2 kg for 40 animals were collected from birth to 52 weeks of age. The Micro‐pig ® is a crossbreed developed by breeding white gilts selected from cross breeds (Korean native pig, Yucatan mini pig, Vietnamese pot‐bellied pig, and Pygmy pig) with Meishan boars. A total of 36 body weight and age data (mean values of 128 animals) ranging from 0.35 to 33.5 kg and 0 to 96 weeks, respectively, were obtained from 20 published experiments and Medi Kinetics (Pyeongtaek, Republic of Korea). Two different nonlinear growth models with 3 parameters in the equation were employed. Estimated body weight growth models of M‐Pig ® as a function of age (week) were: body weight, kg = 64.57 × e −3.21 × e^ ‐0.06t with R 2 = 0.976 in Gompertz model and body weight, kg = 57.94 × (1 + 12.33 × e −0.11 t ) −1 with R 2 = 0.969 in Logistic model. Estimated body weight growth models of Micro‐pig as a function of age (week) were: body weight, kg = 31.47 × e −2.10 × e^ ‐0.07t with R 2 = 0.793 in Compertz model and body weight, kg = 30.45 × (1 + 4.76 × e −0.10 t ) −1 with R 2 = 0.775 in Logistic model. The age at point of inflection in Gompertz model showed that the maximum growth rate of M‐Pig ® and Micro‐pig ® was at 18.9 and 11.2 weeks of age, respectively. The body weight at inflection in Gompertz model of M‐Pig ® and Micro‐pig ® was 23.8 and 11.6 kg, respectively. Taken together, Gompertz models resulted in greater fitness to the growth curve of mini pigs compared with Logistic models. Suggested growth curves for mini pigs may be used for the estimation of body weight gain. Further research is warranted to refine the growth models for mini pigs with a greater amount of data. Support or Funding Information This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2016R1A2B2015665).