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EVALUATION OF HAEMATOLOGICAL PROPERTIES OF WISTAR ALBINO RATS FED Curcuma longa (Turmeric) RHIZOME POWDER
Author(s) -
Iwueke Adaku Vivien,
Ihenacho Kizito,
Nwodu Judith
Publication year - 2017
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.31.1_supplement.974.5
Subject(s) - curcuma , mean corpuscular hemoglobin concentration , rhizome , hemoglobin , traditional medicine , mean corpuscular volume , mean corpuscular hemoglobin , curcumin , oral administration , body weight , distilled water , medicine , pharmacology , zoology , biology , chemistry , chromatography
The nutraceutical spice prepared from turmeric tubers used in many Asian cuisines possesses a diverse array of biological activities including anti‐inflammatory, anti‐neoplastic, and metabolic modifying properties among others. This study investigated the effect of intragastric administration of aqueous suspension of powdered Curcuma longa (turmeric) rhizome on haematological parameters of Wister albino rats. Twenty four male albino rats were randomly divided into four groups (A–D), receiving distilled water, 50 , 100 and 200 mg/kg of the powder respectively for three weeks. The body weights of the animals were measured weekly, while haematological parameters were determined after three weeks. The result revealed that daily oral administration of graded doses of the C. longa powder for the study period showed a non‐significant increase in the body weights of the animals. Treatment with the powder did not significantly ( P ≥ 0.05 ) alter the levels of hemoglobin (Hb), red blood cells (RBC) and means corpuscular volume (MCV) of the rats. The result also showed a significant (p ≤ 0.05) increase in the platelets and mean corpuscular hemoglobin concentrations (MCHC). However, the white blood cells (WBC) and the packed cell volume (PCV) concentrations were slightly reduced. These suggest that turmeric powder at the doses and duration used in the study has no adverse effect on haematological parameters. Support or Funding Information PERSONALY FUNDED