Premium
Relationship Between Vitamin D Status and Cardio‐Metabolic Risk
Author(s) -
Lopez Johanna,
Campa Adriana,
Huffman Fatma G,
Liuzzi Juan P,
Li Tan,
Farooqi Ashar,
Rasul Ammar,
Simoes Herbert,
Lantigua Laura,
Atlas Steven,
Konefal Janet,
Woolger Judi,
Lewis John
Publication year - 2017
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.31.1_supplement.966.12
Subject(s) - vitamin d and neurology , bioelectrical impedance analysis , medicine , anthropometry , photoplethysmogram , arterial stiffness , heart rate variability , autonomic nervous system , cardiology , heart rate , blood pressure , endocrinology , body mass index , filter (signal processing) , computer science , computer vision
The purpose of this study was to investigate the relationship between vitamin D status, measured as serum 25‐hydroxyvitamin D (25(OH)D), and markers of cardiac autonomic function, arterial stiffness and a composite cardio‐metabolic risk score (CMRS), using a novel non‐invasive system. The study enrolled 101 participants, and six were excluded due to missing data (n=95). Participants completed demographic and health history questionnaires, and assessments that included serum 25(OH)D, anthropometrics and CMRS computed by using the ANS‐1 software, which combines three devices (ES‐BC, TM‐Oxi and SudoPath) that use bioelectrical impedance, galvanic skin response, spectrophotometry and an oscillometric blood pressure device to measure body composition, endothelial function, and autonomic nervous system activity markers. Using spearman's correlations, independent t‐tests and multiple linear regressions we found that vitamin D insufficient participants (25(OH)D)<30ng/ml, n=44), compared to vitamin D sufficient individuals (>=30ng/ml, n=51), had significantly lower heart rate variability, and higher photoplethysmography analysis markers and CMRS. These results indicate that vitamin D insufficient participants had decreased cardio‐protective parasympathetic nervous system (PNS) activity, increased endothelian dyfunction markers and were thus, at higher risk of cardio‐metabolic risk, suggesting vitamin D may play a significant role in cardiovascular disease (CVD). Support or Funding Information None