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Non‐ablative radiofrequency enhance collagen content on the injured Achilles tendon after one year in rats
Author(s) -
Akamatsu Flávia Emi,
Itezerote Ana Maria,
Saleh Samir,
Hojaij Flávio,
Andrade Mauro,
Teodoro Walcy
Publication year - 2017
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.31.1_supplement.901.5
Subject(s) - hydroxyproline , tendon , medicine , achilles tendon , surgery , anatomy
Degenerative changes are observed in tendons from people over 35 years of age. Also, Tissue repair in the geriatric patients occurs more slowly than in young adult. The mechanism and effects of radiofrequency (RF) treatment have not yet been described in animal model one year after tendon injury. We investigated the action of RF on the healing process one year after induced experimental lesions of the Achilles tendon in rats. Five adult male Wistar rats weighing between 250 and 300 g were surgically subjected to bilateral partial transverse sectioning of the Achilles tendon. After one year the right tendon was treated with RF (RFT), monopolar RF (Tonederm™) adjusted to 650 kHz and 2 W for two minutes for five days/one week, whereas the left tendon served as control (CT). The tendons were weighed and processed for hydroxyproline content. Statistical analysis used Student t test (α= 5%). We observed a significant increase in hydroxyproline content in treated tendons. Radiofrequency enhances collagen synthesis, suggesting that it can be useful for treatment of chronic tendon lesions.