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The Body Composition Changes and Energy Requirements for Body Weight Gain in Rats
Author(s) -
Inoue Haruna,
Okamura Koji,
Maeda Megumi,
Kondo Emi,
Okumura Yuka,
Miyazaki Shiho
Publication year - 2017
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.31.1_supplement.796.7
Subject(s) - zoology , weight gain , energy expenditure , body weight , basal metabolic rate , composition (language) , lean body mass , adipose tissue , lean tissue , energy requirement , chemistry , medicine , biology , mathematics , statistics , linguistics , philosophy , regression
The relationship between the energy required for body weight (BW) gain and the ratio of increases in the lean body mass (LBM) and the adipose tissue mass (FM) was examined in rats. Rats of 4 weeks of age (n=5, W4 group), 9 weeks of age (n=6, W9 group) and 14 weeks of age (n=6, W14 group) were used. The oxygen consumption and carbon dioxide production were measured for 11 days in the W4 group and for 14 days in the W9 and W14 groups to calculate the energy expenditure. All of the rats had ad libitum access to a standard diet throughout the experiment. Energy deposition was calculated as the difference between energy consumption and energy expenditure during the experimental period. The accretion of the LBM and FM was calculated according to the assumption that the energy content of the LBM and FM was 1400 kcal/kg and 7900 kcal/kg, respectively. The energy required for BW gain was calculated by subtracting the estimated basal metabolic rate (based on the BW) from energy expenditure. The BW gain was 90 g (SD: 9) in the W4 group, 44 g (SD: 11) in the W9 group, and 28 g (SD: 7) in the W14 group. The energy consumption, expenditure and deposition during the experimental period were 797.6 kcal (SD: 48.3), 582.5kcal (SD: 50.1) and 215.1 kcal (SD: 20.7), respectively, in the W4 group; 1231.2 kcal (SD: 69.9), 971.3 kcal (SD: 74.2) and 259.9 kcal (SD: 82.0) in the W9 group; and 1235.7 kcal (SD: 49.7), 1039.6 kcal (SD: 71.6) and 196.1 kcal (SD: 39.7) in the W14 group. The deposition of the LBM and FM was estimated to be 84:16 in the W4 group, 26:74 in the W9 group and 4:96 in the W14 group. The energy required for BW gain during the experiment and for 1 g were calculated to be 292.6 kcal (SD: 43.5) and 3.3 kcal (SD: 0.2), respectively, in the W4 group, 384.3 kcal (SD: 63.8) and 9.4 kcal (SD: 3.2) in the W9 group and 364.6 kcal (SD: 52.7) and 13.8 kcal (SD: 3.6) in the W14 group. A positive correlation was observed between the ratio of FM gain to BW gain and the energy required for BW gain (r=0.81). The estimated energy cost to gain 1 kg of LBM and FM was 3291 kcal and 12,385 kcal, respectively.