Premium
Bioelectrical Impedance Utilization and Dietary Intake Relation in the Analysis of Risk of Lymphedema in Breast Cancer Survivors
Author(s) -
Han Yujin,
Park Hyungseok,
Lim Sungmook,
Lee Seungmin
Publication year - 2017
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.31.1_supplement.790.42
Subject(s) - medicine , bioelectrical impedance analysis , lymphedema , breast cancer , sentinel lymph node , body mass index , axillary lymph node dissection , acromion , cancer , surgery , rotator cuff
Breast cancer survivors are at risk of complications of breast cancer‐related lymphedema (BCRL) after surgery, which may negatively impact the quality of life of breast cancer survivors. The purpose of this study was to investigate bioelectrical impedance analysis (BIA) values from the BIA and the relationship between the occurrence of BCRL and dietary factors. All subjects had a unilateral breast cancer (n =227, 53.16 ± 9.71yr) and underwent surgery at least six month ago. 147 patients had axillary lymph node dissection (ALND) and 80 received sentinel lymph node biopsy (SLNB). BCRL was evaluated based on values from the circumference measurement which was taken at 15cm below the acromion process and 15cm below the olecranon in both arms. BIA, food frequency questionnaire, type of surgery, total number of dissected lymph nodes, and post‐operative treatment were collected. There were approximately 10.7% of breast cancer‐associated lymphedema among the breast cancer survivors. 22 were patients with BCRL and 205 were not (Non‐BCRL). Compared to the Non‐BCRL, the BCRL had higher body mass index (BMI, 25.73 ± 3.59 kg/m 2 and 23.70 ± 4.12 kg/m 2 , p = 0.028), the percent of ideal body weight (PIBW, 121.73 ± 17.34 and 112.21 ± 19.67, p = 0.030), the number of dissected lymph nodes (15.68 ± 9.21 and 7.72 ± 7.01, p = 0.000) and single frequency BIA (SFBIA) ratio (1.145 ± 0.234 and 0.998 ± 0.032, p=0.000). In addition, dietary intake of animal fat and protein intake was found to be greater in the BCRL compared to the Non‐BCRL (p=0.000, p=0.002). Univariate analysis and linear regression analysis demonstrated that BMI, PIBW, the number of dissected lymph nodes, SFBIA ratio and dietary animal fat intake were significant contributors to the occurrence of BCRL. In addition, SFBIA ratio showed 59.09% of sensitivity and 99.09% of specificity to estimate BCRL. In conclusion, our data provide strong evidence to support that obesity‐associated anthropometric and dietary factors are risk factors for the occurrence of BCRL and the use of SFBIA ratio as an alternative method to monitor and/or diagnose BCRL.