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Antioxidant effects of various traditional bioresources in Korea on human dermal fibroblasts cell
Author(s) -
CHOI SUNIL,
Lee Jong Seok,
Lee Sarah,
Kim JaeMin,
Jung TaeDong,
Oh JiWon,
Shin GiHae,
Lee JinHa,
Cho MyoungLae,
Yang HeeSun,
Yeo Joohong,
Kim JongYae,
Lee OkHwan
Publication year - 2016
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.30.1_supplement.lb336
Subject(s) - reactive oxygen species , oxidative stress , antioxidant , chemistry , dpph , hydrogen peroxide , oxidative damage , food science , biochemistry , traditional medicine , medicine
The purpose of this study was to investigate the antioxidant effects of various traditional bioresources in Korea. The results revealed that Castanea crenata Siebold & Zucc. showed the higher total phenolic content (429.11±9.58 mg GAE/g) and NO radical scavenging activity (63.27±0.80%) than those of other bioresources. Furthermore, Rhododendron mucronulatum Turcz. and Cornus officinalis Siebold & Zucc. showed the higher than those of other bioresources in oxygen radical absorbing capacity (1129.79±46.0 μM TE/g) and DPPH radical scavenging activity (21.13±0.25 IC 50 ) each. All of the traditional bioresources markedly reduced the hydrogen peroxide‐induced cell damage, intracellular reactive oxygen species (ROS), and oxidative stress‐induced senescence in human dermal fibroblasts (HDFs). In addition, reactive oxygen species (ROS) are the cause of skin aging, traditional bioresources markedly reduced skin aging. These results indicate that traditional bioresources might have beneficial effects on oxidative stress‐induced damage.