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Rheological Property of Tapioca Maltodextrin‐based Plasma Expander and Effect on Red Blood Cells Morphology
Author(s) -
Chatpun Surapong,
Sawanyawisuth Kittisak,
Piyachomkwan Kuakoon
Publication year - 2016
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.30.1_supplement.947.1
Subject(s) - maltodextrin , rheology , starch , chemistry , viscosity , food science , materials science , chemical engineering , chromatography , spray drying , composite material , engineering
Plasma expanders (PEs) are fluids administered to increase blood volume when blood loss. Hydroxyethyl starch produced from waxy corn starch is one of available plasma expanders. However, it is interesting to look for other potential alternative sources of starch for PEs such as tapioca and potato starches. The aims of this work were to study rheological property of plasma expander prepared from tapioca maltodextrin, a modified tapioca starch, and to investigate its effects on morphology of red blood cells. Tapioca maltodextrin with dextrose equivalent (DE) 1 6 and 12 were used to prepare PEs. Their rheological and physicochemical properties were investigated including viscosity, pH, colloid osmotic pressure and turbidity. Mixture of blood and tapioca maltodextrin plasma expander was sampled and morphology of red blood cells was observed with microscopy technique. The results showed that the degree of DE and the concentration of tapioca maltodextrins affected the rheological and physicochemical properties of PEs. The viscosity of prepared PE was high when the degree of DE was low whereas the increase of concentration enhanced viscosity of PEs. It was also found that PE prepared from 10% w/v tapioca maltodextrin with DE6 (10% DE6) had nearly similar rheological property to 6% hydroxyethyl starch 130/0.4. Furthermore, high concentration of tapioca maltodextrin altered a shape of red blood cells, especially at high concentration. Stability of viscosity for 10% DE6 plasma expander was in an acceptable range. Tapioca maltodextrin with DE6 has a possibility to be prepared as PEs. However, it is still necessary to continually research and investigate the effects of this PE in animal models. Support or Funding Information Funding was supported by Prince of Songkla University (Grant No. MED560351S), Faculty of Medicine and the Thailand Research Fund (Grant No. MRG5680044).The relationship between concentration and viscosity of tapioca maltodextrin solutions.