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Tomato based supplement supports cardiovascular health
Author(s) -
Hermoni Karin Linnewiel,
Shefer Irit,
Raz Golan
Publication year - 2016
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.30.1_supplement.913.5
Subject(s) - medicine , meal , oxidative stress , diabetes mellitus , obesity , placebo , insulin , lipid profile , cholesterol , carotenoid , cardiovascular health , endothelial dysfunction , endocrinology , blood pressure , food science , disease , biology , alternative medicine , pathology
Tomato rich diet is linked to favorable effects on cardiovascular health. The effects of tomato carotenoids on various parameters related to cardiovascular health such as blood pressure, endothelial function, inflammation and oxidative stress have been the subject of extensive research. The Aim of the current clinical study was to investigated the effects of tomato extract consumption on the management of post prandial lipid and sugar profiles. Consumption of a high fat meal causes a stress reaction that includes transient rise in triglycerides as well as an elevation in glucose and insulin levels. Oxidative stress associated with the high‐fat meal has been suggested as a major contributor to the pathogenesis of atherosclerosis along with other chronic disease states such as diabetes and obesity. One mechanism is the increased oxidation of LDL cholesterol, which promotes plaque formation and increases cardiovascular risk. The current clinical trial included 150 healthy men and women that were supplemented for 2 weeks with Cardi‐O‐Mato (tomato based product) or placebo. At the end of supplementation period, subjects consumed a high fat meal and parameters related to lipid and sugar profile as well as oxLDL levels were evaluated. Interestingly, volunteers who consumed the tomato supplement had significantly reduced levels of oxidized LDL compared to placebo group. Moreover, insulin levels were reduced following supplementation. A beneficial trend was also observed for post‐meal glucose levels. This study suggests that tomato phytonutrients possess a favorable effect on various aspects related to cardiovascular health and management of high fat meal‐induced stress. Support or Funding Information This study was founded by Lycored Ltd